The aim of this 5-days course is to establish a forum for the community carrying out research on the family of poly(ADP-ribose) polymerases (PARPs) in the form of a bi-annual reunion in an intercalating fashion to the CSHL PARP meetings that are held every even year. The topics will cover all PARP-related fields from basic molecular and physiological studies to applied clinical research with an explicit aim to cover drug development and clinical studies. The program includes lectures, round table discussions, oral presentations and poster sessions. All this is organized in a way that facilitates the interaction of the students/young researchers with the experts in the different topics included in the course. The meeting is expected to host ~100 participants encompassing scientists engaged in drug chemistry, protein crystallography, protein and nucleic acid (bio)chemistry, transcriptomics, DNA repair, animal and human studies.