Symposium Overview

RNA biology is intimately interlinked with DNA metabolism on multiple levels, and the crosstalk between the two nucleic acids involves potential for both conflicts as well as cooperative relationships. On the one hand, gene expression poses a considerable risk for genome maintenance and vice versa. On the other hand, the machineries involved in RNA and DNA transactions are known to cooperate in several important aspects of nuclear biology. This symposium will bring together scientists studying genome maintenance and the DNA damage response with those investigating the biology of transcription and RNA biology in order to discuss these mutual interactions of DNA and RNA metabolism.