Aging is a major risk factor for the development of organ dysfunction and disease. Although under debate, there exists a strong association between decline in stem cell function, possibly impinging on the selection of mutant stem cells, impairments in tissue maintenance and disease development during aging. The G-JAM will discuss basic concepts and therapeutic targets on the causes and consequences of stem cell during organism aging.

Principal themes and objectives of the meeting

The G-JAM fosters interaction of researchers engaged in the study of basic principles of stem cell and tissue maintenance in aging. The meeting will focus on basic molecular and genetic processes that affect genetic and epigenetic stability, protein homeostasis and metabolic processes - thereby impairing the functionality and self-renewal of stem cells and organ maintenance.

The main aim of the G-JAM is to increase our understanding of organism aging.

Scientific Sessions

• Mitochondria and Protein Homeostasis

• Systemic and Niche Factors

• Epigenetics, DNA Damage, Genome Integrity

• Stem Cells and Regeneration

• Interventions